EB Medical Research is led by a small, highly experienced team with a direct hand in every study we run. Our feasibility assessments are never routed through layers of approval — they go straight to the three people who can actually answer a sponsor’s questions: Mazin Alhakim for the medical and pharmacological fit, Barbara Dormans for operational and recruitment feasibility, and Robert Kimman for the financial and legal terms. This structure means feasibility responses and contracting decisions can move quickly, without a sponsor having to wait for input to work its way up an organization.
Principal Investigator
After completing his medical studies, Mazin started as a research physician in Utrecht in 2000, joining EB Medical Research as Principal Investigator in 2004. With over 25 years of clinical trial experience across a broad range of indications, he brings deep insight into new treatment methods and a sharp read on how a trial is actually progressing for its subjects, allowing him to give sponsors a well-founded assessment of fit at the feasibility stage.
Principal Investigator
Director Operations
Barbara joined EB Medical Research in 2007 as a study coordinator, working closely on the operational and recruitment side of clinical trials. In 2020, she and co-owner Robert Kimman took over the company through a management buy-out. As Director of Operations, she is directly involved in the planning, design, recruitment and execution of every study, giving her close, current knowledge of what is happening across the portfolio at any given time.
Director Operations
Business Director
Robert brings extensive financial leadership experience. From 2015, he served as Director of EB Medical Research. In November 2020, he and Barbara Dormans took over EB Medical Research through a management buy-out. As Business Director, he is closely involved in the operational process and responsible for the legal and financial aspects of every study, which allows contracting processes to be completed quickly.
Business Director
Sub Investigator
Raphael Tan is EB Medical Research's permanent Sub-Investigator, serving as backup for Mazin Alhakim.
Sub Investigator
Pharmacist
Pharmacist Tuyen Nguyen, through his company Pharmaserv, has been EB Medical Research's permanent pharmacist since 2010, building extensive experience with pharmacy operations in clinical trials over that time.
Pharmacist
EB Medical Research operates under a structured quality management framework covering training, documentation, data protection and regulatory compliance, across every study we conduct.
All site staff involved in clinical trials are trained and certified to ICH GCP E6(R3), with recertification on a recurring cycle to stay current as the guideline evolves. Dedicated blinded and unblinded study teams are used where a study requires it, with the blinded team also responsible for participant-facing procedures such as app and questionnaire instructions.
Our operations are governed by a documented set of Standard Operating Procedures covering the full trial lifecycle, from participant recruitment and informed consent through to data storage, equipment calibration, and archiving after study close-out. SOPs are formally reviewed on a two-year cycle, with a named owner and dual sign-off for every version.
Deviations from a protocol, SOP or GCP requirement are documented through a formal Non-Conformity procedure, with root-cause analysis and a CAPA (Corrective and Preventive Action) plan for every finding, including an explicit assessment of whether a deviation constitutes a Serious Breach.
Personal and health-related data of research candidates and subjects is processed in accordance with the GDPR / AVG, under the oversight of a designated Data Protection Officer. Access to digital participant data is restricted to authorized personnel. Candidates in our recruitment database provide explicit, opt-in consent before being approached about study participation, and can withdraw that consent at any time. A documented data breach procedure is in place.
The site management holds HACCP certification, covering the safe handling, storage and preparation of food products and supplements used in nutrition studies.
Clinical research at EB Medical Research is conducted in accordance with the Medical Research Involving Human Subjects Act (WMO). Studies requiring ethical review are submitted to an accredited Medical Research Ethics Committee (METC), under oversight of the CCMO, the Dutch national body responsible for the ethical and scientific review of medical research.
Study documentation is archived with an accredited, security-certified archiving partner for a period defined by applicable regulation: 25 years for pharmaceutical research, 30 years for advanced therapy medicinal products, 15 years for implantable medical devices (10 years for other medical device research), and 15 years for other WMO-regulated research. All archived data remains the property of the sponsor.
Critical measurement equipment, including centrifuges, ECG devices and blood pressure monitors, is calibrated on a scheduled basis by accredited external technicians, with certificates retained on file. Temperature-controlled storage equipment, including -80°C freezers, is maintained under a scheduled service contract, with 24/7 remote temperature monitoring and alerting, and backup freezer capacity available in the event of equipment failure.
EB Medical Research maintains a mutual, independent complaints officer arrangement with Delphinium, ensuring participant complaints are handled independently of the site conducting the study.